Amidotrizoate

The X-ray contrast media that contain Amidotryzoic acid or its compounds diatrizoate and meglumine or sodium amidotrizoatehave a content of Iodine from 47% to 62%. Intravenous administration.

Amidotryzoate excretion into breast milk is nil ^{(Fitzjohn 1982)} or in clinically non-significant amount,  < 0.1% of maternal dose. ^{(Texier 1983, Weyrauch 1977)}

Several medical societies and expert authors consider the use of this medication to be safe or very probably safe during breastfeeding ^{(Hale, Briggs 2015)}. American Academy of Pediatrics: medication usually compatible with breastfeeding ^{(AAP 2001)}. Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs: compatible with Breastfeeding. ^{(WHO 2002)}

The various Iodinated contrast media for imaging examinations (X-rays, CT scans) are considered compatible with breastfeeding since they are rapidly eliminated with little or no release of iodine, not metabolized and virtually not absorbed when taken by mouth. They are structurally very similar to each other and one of them is their data no or minimal excretion in milk.

Given the low lipid solubility of the iodinated contrast, less than 1% of the dose administered to the mother just passing milk. Due to their low oral bioavailability, intestinal absorption is less than 1% of the dose that he may take the infant. The maximum dose just getting the baby is less than 0.01% of the maternal dose, which represents less than 1% of the dose administered to a nursing practice that is a radiological contrast examination.

Most experts and radiology scientific societies agree that after a radiological iodinated contrast examination is not necessary to wait no time to nurse.

 

See below the information of this related product:

• (Iodide Radiopaque Agent) (Safe substance and/or breastfeeding is the best option.)