Last update Feb. 12, 2025

Algeldrate

Compatible

Safe product and/or breastfeeding is the best option.

Aluminum hydroxide or algeldrate is an antacid used for the symptomatic relief of heartburn, acid indigestion, and upset stomach. Oral administration.

Aluminum from antacids is not concentrated in breast milk. (Mahadevan 2006, Richter 2005)

After intake of aluminum-containing antacids, plasma aluminum values rise from basal 7 μg/L to 55 μg/L within half an hour and then fall back to their previous value 3 hours later.

Although trace amounts of aluminum may be found in milk, it has no adverse effects on the infant. Breast milk contains an average of 49 μg/L aluminum, much lower than the 180-700 μg/L in artificial formulas. (Burrell 2010, Simmer 1990)

Its low oral bioavailability means that the passage to infant plasma from ingested breast milk is scarce, except in premature infants and immediate neonatal period, in which there may be greater intestinal absorption.

The manufacturer and expert authors consider its use compatible with breastfeeding. (Hale, AEMPS 2014, Mahadevan 2006, Richter 2005, Broussard 1998)

Avoid chronic or excessive use. List of essential medicines WHO 2002: Compatible with breastfeeding. (WHO 2002)

Alternatives

We do not have alternatives for Algeldrate since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Algeldrate is also known as


Algeldrate in other languages or writings:

Group

Algeldrate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Algeldrate in its composition:

  • Acyline™. Contains other elements than Algeldrate in its composition
  • Algicon™. Contains other elements than Algeldrate in its composition
  • Alkagel Complex™. Contains other elements than Algeldrate in its composition
  • Alu-Cap
  • Alu-Tab
  • Alucol
  • Aludrox
  • Aludrox II™. Contains other elements than Algeldrate in its composition
  • Alugel
  • Amphojel
  • Aziram
  • Basaljel
  • Dracone™. Contains other elements than Algeldrate in its composition
  • Flogodisten™. Contains other elements than Algeldrate in its composition
  • Gasopax™. Contains other elements than Algeldrate in its composition
  • Gastrobion™. Contains other elements than Algeldrate in its composition
  • Gastrogel™. Contains other elements than Algeldrate in its composition
  • Gelodrox™. Contains other elements than Algeldrate in its composition
  • Kolantyl™. Contains other elements than Algeldrate in its composition
  • Kompensan
  • Lenicet™. Contains other elements than Algeldrate in its composition
  • Maalox Plus™. Contains other elements than Algeldrate in its composition
  • Merankol Pastiglie™. Contains other elements than Algeldrate in its composition
  • Nephrox
  • Nogastra™. Contains other elements than Algeldrate in its composition
  • Nulacid™. Contains other elements than Algeldrate in its composition
  • Pepsamar
  • Plusgel™. Contains other elements than Algeldrate in its composition
  • Polysilane Delalande™. Contains other elements than Algeldrate in its composition
  • Ulgel™. Contains other elements than Algeldrate in its composition

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 17 -30 %
Molecular weight 78 daltons

References

  1. Hale TW. Medications & Mothers' Milk. 1991- . Springer Publishing Company. Available from https://www.halesmeds.com Consulted on April 10, 2024 Full text (link to original source)
  2. AEMPS. Algeldrato. Ficha técnica. 2014 Full text (in our servers)
  3. Burrell SA, Exley C. There is (still) too much aluminium in infant formulas. BMC Pediatr. 2010 Abstract Full text (link to original source) Full text (in our servers)
  4. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  5. Richter JE. Review article: the management of heartburn in pregnancy. Aliment Pharmacol Ther. 2005 Nov 1;22(9):749-57. Review. Abstract Full text (in our servers)
  6. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)
  7. Broussard CN, Richter JE. Treating gastro-oesophageal reflux disease during pregnancy and lactation: what are the safest therapy options? Drug Saf. 1998 Oct;19(4):325-37. Review. Abstract
  8. Nagy E, Jobst K. The kinetics of aluminium-containing antacid absorption in man. Eur J Clin Chem Clin Biochem. 1994 Abstract
  9. Simmer K, Fudge A, Teubner J, James SL. Aluminum concentrations in infant formulae. J Paediatr Child Health. 1990 Abstract
  10. Cruikshank DP, Varner MW, Pitkin RM. Breast milk magnesium and calcium concentrations following magnesium sulfate treatment. Am J Obstet Gynecol. 1982 Jul 15;143(6):685-8. No abstract available. Abstract

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