Last update Aug. 31, 2021
Very Low Risk
Antiviral very active against Herpes Simplex and varicella-zoster herpesvirus.
Intravenous, oral and topical (dermatological and ophthalmological) administration.
Authorized use in newborns and infants.
Despite its higher concentration in breast milk than in plasma (Mactal 2001,Bork 2000, Lau 1987), it is excreted in breast milk in clinically insignificant amounts, much lower than the dose used in newborns and infants (Drake 2012, Bork 1995, Taddio 1994, Don 1991, Meyer 1988, Lau 1987), and no problems have been observed in infants whose mothers were taking acyclovir (Agarwal 2019, Taddio 1994).
Systemic absorption of topical cutaneous acyclovir is negligible (Mactal 2001).
List of WHO essential medicines: compatible with breastfeeding (WHO / UNICEF 2002).
American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).
We do not have alternatives for Acyclovir since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.
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