Last update Jan. 16, 2021

Acetohexamide

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Sulfonylurea that stimulates endogenous insulin secretion. May cause hypoglycemia.
Indicated in the treatment of type 2 diabetes.
Oral administration.

We did not find published data regarding the excretion of this substance through breast milk at the time this last update was completed.

It has been withdrawn from the market (Briggs 2015).

Diet, exercise, and breastfeeding improve blood sugar levels.

Alternatives

  • Glibenclamide (Safe product and/or breastfeeding is the best option.)
  • Hypocaloric Diet (Safe product and/or breastfeeding is the best option.)
  • Insulin (Safe product and/or breastfeeding is the best option.)
  • Maternal Sport (Safe product and/or breastfeeding is the best option.)
  • Metformin Hydrochloride (Safe product and/or breastfeeding is the best option.)
  • Tolbutamide (Safe product and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
DONATE NOW

Other names

Acetohexamide in other languages or writings:

Group

Acetohexamide belongs to this group or family:

Tradenames

Main tradenames from several countries containing Acetohexamide in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 90 %
Molecular weight 324 daltons
Protein Binding 90 %
VD 0.2 l/Kg
pKa 4.3 -
Tmax 5 hours
T½ 5 - 6 hours

References

  1. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015

Total visits

6,440

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write us at elactancia.org@gmail.com

e-lactancia is a resource recommended by Amamanta of Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM