Last update April 18, 2025

Aceclofenac

Compatible

Safe product and/or breastfeeding is the best option.

Nonsteroidal anti-inflammatory (NSAID) drug similar to diclofenac, used in the treatment of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Oral administration twice daily.

At the date of the last review, we found no published data on breastfeeding.

Its high binding to plasma proteins and large volume of distribution make it unlikely to pass into milk. Diclofenac, from the same family of anti-inflammatory drugs, is eliminated in non-significant quantities in breast milk and is considered compatible with breastfeedin. (Hutchinson 2013)

Alternatives

  • Diclofenac (Safe product and/or breastfeeding is the best option.)
  • Ibuprofen (Safe product and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

Aceclofenac in other languages or writings:

Group

Aceclofenac belongs to this group or family:

Tradenames

Main tradenames from several countries containing Aceclofenac in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 354 daltons
Protein Binding > 99 %
VD 0.36 l/Kg
pKa 3.44 -
Tmax 1 - 3 hours
T½ 4 hours

References

  1. Hutchinson S, Marmura MJ, Calhoun A, Lucas S, Silberstein S, Peterlin BL. Use of common migraine treatments in breast-feeding women: a summary of recommendations. Headache. 2013 Abstract Full text (link to original source) Full text (in our servers)
  2. Aceclofenac Data Sheet 2009 Full text (in our servers)
  3. Aceclofenaco Ficha técnica 2007 Full text (in our servers)
  4. Hirose M, Hara Y, Hosokawa T, Tanaka Y. The effect of postoperative analgesia with continuous epidural bupivacaine after cesarean section on the amount of breast feeding and infant weight gain. Anesth Analg. 1996 Abstract

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