Last update: Jan. 10, 2015

Suxamethonium Chloride

Very Low Risk for breastfeeding


Safe. Compatible.
Minimal risk for breastfeeding and infant.

Muscle-relaxant agent with a peripheric depolarizing action that is used for rapid endotracheal intubation procedures, which also has a transient effect.

At latest update, no relevant published data concerning excretion into breast milk were found.

Because of a very rapid half-life elimination period (less than 1 minute), a significant excretion into breast milk is unlikely.

Also, a low oral bioavailability renders the pass of this agent to the infant's plasma, highly unlikely.

Succinylcholine should not prevent a mother from breast feeding her baby shortly after recovering from an anesthesia if she is in a good condition.

List of Medicines (WHO-2002): compatible with Breastfeeding.

Alternatives

We do not have alternatives for Suxamethonium Chloride since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Suxamethonium Chloride belongs to this group or family:

Tradenames

Main tradenames from several countries containing Suxamethonium Chloride in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. ≈ 0 %
Molecular weight 397 daltons
T1/2 0,013 hours

References

  1. Howie WO, McMullen PC. Breastfeeding problems following anesthetic administration. J Perinat Educ. 2006 Abstract Full text (link to original source) Full text (in our servers)
  2. Sener EB, Guldogus F, Karakaya D, Baris S, Kocamanoglu S, Tur A. Comparison of neonatal effects of epidural and general anesthesia for cesarean section. Gynecol Obstet Invest. 2003 Abstract
  3. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  4. Kato M, Shiratori T, Yamamuro M, Haga S, Hoshi K, Matsukawa S, Jalal IM, Hashimoto Y. Comparison between in vivo and in vitro pharmacokinetics of succinylcholine in humans. J Anesth. 1999 Abstract
  5. Torda TA, Graham GG, Warwick NR, Donohue P. Pharmacokinetics and pharmacodynamics of suxamethonium. Anaesth Intensive Care. 1997 Abstract
  6. Spigset O. Anaesthetic agents and excretion in breast milk. Acta Anaesthesiol Scand. 1994 Abstract
  7. Hoshi K, Hashimoto Y, Matsukawa S. Pharmacokinetics of succinylcholine in man. Tohoku J Exp Med. 1993 Abstract Full text (link to original source) Full text (in our servers)

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