Last update: Nov. 24, 2016


Very Low Risk for breastfeeding

Safe. Compatible.
Minimal risk for breastfeeding and infant.

Proteolytic and lipolytic enzyme which is derived from mammalian pancreas that has protease, lipase and amylase activity. Indicated for treatment of cystic fibrosis and chronic pancreatitis.

At latest update no published data on excretion into breast milk was found.

Its high molecular weight and poor intestinal absorption make it highly unlikely a significant passage to the milk.
A low oral bioavailability hinders the passage into infant plasma from ingested milk.

It is a medication used in children and young infants.


We do not have alternatives for Pancreatin since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Pancreatin is also known as

Pancreatin in other languages or writings:


Main tradenames from several countries containing Pancreatin in its composition:


Variable Value Unit
Oral Bioavail. 0 %
Molecular weight 43.000 - 50.000 daltons
Tmax 0,5 hours
T1/2 3 hours


  1. BGP. Pancreatine. Product Monograph. 2014 Full text (in our servers)
  2. AEMPS. Pancreatina. Ficha técnica. 2012 Full text (in our servers)
  3. Colombo C, Fredella C, Russo MC, Faelli N, Motta V, Valmarana L, Longo L, D'Orazio C. Efficacy and tolerability of Creon for Children in infants and toddlers with pancreatic exocrine insufficiency caused by cystic fibrosis: an open-label, single-arm, multicenter study. Pancreas. 2009 Abstract

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e-lactancia is a resource recommended by La Liga de la Leche de Euskadi

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