Last update: Oct. 15, 2014

Mefloquine

Very Low Risk for breastfeeding


Safe. Compatible.
Minimal risk for breastfeeding and infant.

Minimally secreted into breast milk

Not commercially available in Spain

Alternatives

We do not have alternatives for Mefloquine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Mefloquine belongs to this group or family:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 85 %
Molecular weight 415 daltons
Protein Binding 98 %
Tmax 2 hours
T1/2 504 hours
M/P ratio 0,2 -
Theoretical Dose 0,008 mg/Kg/d
Relative Dose 0,04 %
Relat.Ped.Dose 0,03 - 1,6 %

References

  1. Arguin PM, Tan KR. Chemoprophylaxis during Pregnancy and Breastfeeding In Chapter 3. Infections diseases related to travel. Malaria. In Centers for Disease Control and Prevention. CDC Health Information for International Travel 2014. 2014 Full text (link to original source) Full text (in our servers)
  2. Chen LH, Zeind C, Mackell S, LaPointe T, Mutsch M, Wilson ME. Breastfeeding travelers: precautions and recommendations. J Travel Med. 2010 Jan-Feb;17(1):32-47. Abstract Full text (link to original source) Full text (in our servers)
  3. Pérez JL, Carranza C, Mateos F. Antiparasitarios. Revisión de los fármacos útiles en el tratamiento de parasitosis clásicas y emergentes. \ [Antiparasitic drugs. Review of the useful drugs in the treatment of classic and emergent parasitic diseases]. Rev Esp Quimioter. 2009 Jun;22(2):93-105. Review. Spanish. Abstract Full text (link to original source) Full text (in our servers)
  4. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM