Last update: Aug. 19, 2019

Maternal Tuberculosis

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Whether a mother has been diagnosed and treated during pregnancy, or, diagnosed after birth: It makes no sense to wean the baby. On the first instance, the mother is not contagious any longer. On the second one, the baby has been already exposed to infection.

On cases when diagnosis were attained later than 15 days before delivery: Treat the mother, delay breastfeeding and infant-to-mother contact for 15 days. Meanwhile, milk must be pumped-out and given to the infant if the mother does not have active lesions on the breast.

Except on those rather rare cases of mammary tuberculosis abscesses, TB bacilli have not been found in breast milk. Anti-TB therapy is compatible with breastfeeding.

The infant must undergo a tuberculin skin test (PPD), chest x-Ray examination, and receive chemoprophylaxis (adjust isoniacid given to the child to the lowest dose since it is largely secreted into breast milk).


See below the information of these related products:

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Maternal Tuberculosis is also known as


Group

Maternal Tuberculosis belongs to this group or family:

References

  1. Garessus EDG, Mielke H, Gundert-Remy U. Exposure of Infants to Isoniazid via Breast Milk After Maternal Drug Intake of Recommended Doses Is Clinically Insignificant Irrespective of Metaboliser Status. A Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach to Estimate Drug Exposure of Infants via Breast-Feeding. Front Pharmacol. 2019 Jan 22;10:5. Abstract
  2. Partosch F, Mielke H, Stahlmann R, Gundert-Remy U. Exposure of Nursed Infants to Maternal Treatment with Ethambutol and Rifampicin. Basic Clin Pharmacol Toxicol. 2018 Aug;123(2):213-220. Abstract
  3. Click ES, Ouma GS, DeGruy K, Murithi W, Okonji JA, McCarthy KD, Musau S, Okumu A, Alexander H, Posey J, Cain KP. No evidence of Mycobacterium tuberculosis in breast milk of 18 women with confirmed TB disease in Kisumu, Kenya. Int J Tuberc Lung Dis. 2018 Apr 1;22(4):464-465. Abstract
  4. Di Comite A, Esposito S, Villani A, Stronati M; Italian Pediatric TB Study Group. How to manage neonatal tuberculosis. J Perinatol. 2016 Abstract
  5. Lawrence RA, Lawrence RM. Breastfeeding. A guide for the medical profession. Eighth Edition. Philadelphia: Elsevier; 2016
  6. Baquero-Artigao F, Mellado Peña MJ, del Rosal Rabes T, Noguera Julián A, Goncé Mellgren A, de la Calle Fernández-Miranda M, Navarro Gómez ML; Working Group on gestational, congenital, and postnatal tuberculosis, Spanish Society of Pediatric Infectious Diseases (PFIC). Guía de la Sociedad Española de Infectología Pediátrica sobre tuberculosis en la embarazada y el recién nacido (ii): profilaxis y tratamiento. [Spanish Society for Pediatric Infectious Diseases guidelines on tuberculosis in pregnant women and neonates (ii): Prophylaxis and treatment]. An Pediatr (Barc). 2015 Abstract Full text (link to original source) Full text (in our servers)
  7. Mittal H, Das S, Faridi MM. Management of newborn infant born to mother suffering from tuberculosis: current recommendations & gaps in knowledge. Indian J Med Res. 2014 Abstract Full text (link to original source) Full text (in our servers)
  8. Red Book. Pickering LK, Baker CJ, Kimberlin DW, Long SS, eds. Red Book: 2012 Report of the Committee on Infectious Diseases. 29th ed. Elk Grove Village, Red Book 2012
  9. Singh N, Golani A, Patel Z, Maitra A. Transfer of isoniazid from circulation to breast milk in lactating women on chronic therapy for tuberculosis. Br J Clin Pharmacol. 2008 Abstract Full text (link to original source) Full text (in our servers)
  10. WHO: World Health Organization Stop TB Partnership Childhood TB Subgroup. Chapter 4: childhood contact screening and management. Int J Tuberc Lung Dis. 2007 Abstract Full text (in our servers)
  11. Drobac PC, del Castillo H, Sweetland A, Anca G, Joseph JK, Furin J, Shin S. Treatment of multidrug-resistant tuberculosis during pregnancy: long-term follow-up of 6 children with intrauterine exposure to second-line agents. Clin Infect Dis. 2005 Jun 1;40(11):1689-92. Epub 2005 Apr 18. Abstract Full text (link to original source) Full text (in our servers)
  12. Blumberg HM, Burman WJ, Chaisson RE, Daley CL, Etkind SC, Friedman LN, Fujiwara P, Grzemska M, Hopewell PC, Iseman MD, Jasmer RM, Koppaka V, Menzies RI, O'Brien RJ, Reves RR, Reichman LB, Simone PM, Starke JR, Vernon AA; American Thoracic Society, Centers for Disease Control and Prevention and the Infectious Diseases Society. American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: treatment of tuberculosis. Am J Respir Crit Care Med. 2003 Abstract Full text (link to original source) Full text (in our servers)
  13. ATC (American Thoracic Society); CDC; Infectious Diseases Society of America. Treatment of tuberculosis. MMWR Recomm Rep. 2003 Abstract Full text (link to original source) Full text (in our servers)
  14. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  15. Tran JH, Montakantikul P. The safety of antituberculosis medications during breastfeeding. J Hum Lact. 1998 Dec;14(4):337-40. Review. Abstract
  16. WHO. Breastfeeding and maternal tuberculosis. Division of Child Health and development. 1998 Full text (in our servers)
  17. Dautzenberg B, Grosset J. [Tuberculosis and pregnancy]. Rev Mal Respir. 1988 Abstract
  18. Snider DE Jr, Powell KE. Should women taking antituberculosis drugs breast-feed? Arch Intern Med. 1984 Abstract

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