Last update: Jan. 10, 2015

Hydrocortisone Topical Use

Very Low Risk for breastfeeding


Safe. Compatible.
Minimal risk for breastfeeding and infant.

Topical use: Because of a low absorption through skin, a significant excretion into breast milk is unlikely. Additionally, a high protein binding makes excretion even more unlikely.

Whenever a treatment for nipple eczema or dermatitis is required the lowest potency steroid compound should be used. It should be applied right after the feed to make sure it has disappeared before the next nursing occurs. Otherwise, wipe cream out with a clean gauze. Do not continuously use for longer than a week.

Reportedly, a case of mineral-steroid toxicity has occurred due to continuous use of cream on the nipple.

Creams, gels or similar products that contain paraffin or mineral oil should not be used on the nipple to avoid absorption by the infant.

Alternatives

We do not have alternatives for Hydrocortisone Topical Use since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
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Other names

Hydrocortisone Topical Use is also known as


Group

Hydrocortisone Topical Use belongs to this group or family:

Tradenames

Main tradenames from several countries containing Hydrocortisone Topical Use in its composition:

List of 19 tradenames
  • Aquacort™
  • Cohortan™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Cortisporin Ointment™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Cristalomicina™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Dermo Hubber™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Hemorrane™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Isdinium™
  • Kinogen (Italy)™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Lactisona™
  • Oralsone adultos™
  • Proctol™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Proctomyxin HC™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Proctosedyl™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Proktosedon™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Shericur™
  • Suniderma™
  • Uniroid-HC™. Contains other elements than Hydrocortisone Topical Use in its composition
  • Westcort™
  • ratio-Proctosone™. Contains other elements than Hydrocortisone Topical Use in its composition

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 96 %
Molecular weight 363 daltons
Protein Binding 90 %
T1/2 2 hours

References

  1. AEMPS. Hidrocortisona tópica. Ficha técnica. 2010 Full text (link to original source) Full text (in our servers)
  2. Concin N, Hofstetter G, Plattner B, Tomovski C, Fiselier K, Gerritzen K, Fessler S, Windbichler G, Zeimet A, Ulmer H, Siegl H, Rieger K, Concin H, Grob K. Mineral oil paraffins in human body fat and milk. Food Chem Toxicol. 2008 Abstract
  3. Noti A, Grob K, Biedermann M, Deiss U, Brüschweiler BJ. Exposure of babies to C15-C45 mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003 Abstract
  4. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  5. Nice FJ, Snyder JL, Kotansky BC. Breastfeeding and over-the-counter medications. J Hum Lact. 2000 Nov;16(4):319-31. Review. Erratum in: J Hum Lact 2001 Feb;17(1):90. Abstract
  6. Bodley V, Powers D. Long-term treatment of a breastfeeding mother with fluconazole-resolved nipple pain caused by yeast: a case study. J Hum Lact. 1997 Abstract
  7. De Stefano P, Bongo IG, Borgna-Pignatti C, Severi F. Factitious hypertension with mineralocorticoid excess in an infant. Helv Paediatr Acta. 1983 Abstract

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