Last update: Feb. 27, 2018
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
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First generation antihistaminic and alchylamine drug, with sedative effect. Its active isomer is Dexchlorfeniramine.
Oral dosage every 4-6 hours
Since the last update we have not found published data on its excretion in breast milk.
No problems requiring medical attention have been observed in infants of mothers taking chlorpheniramine (Ito 1993, Paton 1985).
Likely inhibition of lactation within the first weeks post delivery because anti-prolactin effect (WHO 2002, Messinis 1985).
Short-term and low dose (2 mg one or twice-day) treatment is compatible with breastfeeding (Lactmed 2017).
Follow-up for sedation and feeding ability of the infant (Butler 2014, WHO 2002).
For long-term treatment an alternative drug should be preferred (Powell 2007).
Compounds in association with expectorants, corticoids and cough relief medicines are available. Avoid drug associations especially while breastfeeding.
Bed-sharing is not recommended for mothers who are taking this medication (UNICEF 2013, Landa 2012, ABM 2008, UNICEF 2006).
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Confederación Nacional de Pediatría (CONAPEME) from Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM