Last update: Dec. 19, 2013

Alosetron

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Cases of severe intestinal side effects have been reported.

On latest update no published data about breastfeeding were found. Because a rapid metabolic rate and poor oral absorption - when taken along with food - this drug is probably safe while breastfeeding. Safety would increase if a 3-hour period is observed before resuming breastfeeding.

Alternatives

We do not have alternatives for Alosetron.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Alosetron belongs to this group or family:

Tradenames

Main tradenames from several countries containing Alosetron in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 60 %
Molecular weight 294 daltons
Protein Binding 82 %
Tmax 1 hours
T1/2 1,5 hours

References

  1. Alosetron Data Sheet 2010 Full text (in our servers)
  2. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  3. Andresen V, Hollerbach S. Reassessing the benefits and risks of alosetron: what is its place in the treatment of irritable bowel syndrome? Drug Saf. 2004 Abstract

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